The partial thromboplastin time: reply

Laboratory Methodologic Approach in Prolonged Activated Partial Thromboplastin Time Test

The pathological activated partial thromboplastin time test is a data that we can find in all clinical laboratories routinely. The hemato-coagulative clinical case here reported aims to point out how the laboratory can provide a correct diagnosis by methodological rational setting and, consequently, carry out an appropriate therapy, or reassure the patient that the pathological data will not ca...

The partial thromboplastin (cephalin) time test.

Nine partial thromboplastin (cephalin) reagents have been compared in a parallel investigation of groups of patients on ;long-term' anticoagulants, a group with moderate haemophilia, and patients on heparin infusion. Results with the seven commercial reagents and a human cephalin extract have been correlated with those of a specially prepared and standardized reference preparation of human brai...

A further face of the partial thromboplastin time APTT.

Some variables which influence the activated partial thromboplastin time assay.

‘ITHE partial thromboplastin time assay (PTT) as developed by Langdell et al. (1) has proved to be a very usef ul test for studying the coagulatioll mechanism silice it C 11 reveal tile al)SellCe of any factor except Factor VII and platelets. lnder rigorously cOlitrolled COll(litiOlIS, the reproducibility of tile test is satisfactory. However, any change ill tile surface of the svl’inge, test t...

Detection of factor VIII inhibitors with the partial thromboplastin time.

Variations of the partial thromboplastin time (PTT) were tested to determine the best screening method for detection of inhibitors of factor VIII. Variables tested included the duration of preincubation of a mixture of patient plasma and factor VIII source (normal plasma), the ratio of the patient plasma to the normal plasma, and the duration of incubation of the normal plasma-patient plasma mi...